For half frame good enough, roughly near/mid/far and you are good. On 35mm this is not more tricky, but still doable.
The old folders until the 1950s used in most cases zone focus for medium format up to 6×9, I guess in this case you work just with f8 and smaller to get the focus right.

I realized something similar when first time looking at the photos from my new Minolta MD 20/2.8 where I expected something crazy wide: It somehow looked not too strange/unusual! I had seen this before when using my Pentax 6456 with a 35mm and 33-55mm lenses, but thought somehow the different image ratio influence it.
But no: Cell phone cameras totally made us used to ultra-wide angle photos…

I think with most of my cameras I still use more horizontal, but using my halfframe (Canon Demi EE17) which is in portrait orientation was definitely not strange.

You could look at bulk loading, or even splitting a store-bought roll of film into two or three parts and splicing that onto an empty film roll.
Beside the cost savings, I think being able to choose your number of frames is one of the best aspects of bulk loading.

Just build a new espio mini, you cowards!